The application of proteomics to diabetes.

Application of Bayesian Latent Variable Model for Early Detection of Gestational Diabetes Mellitus Without A Perfect Reference Standard Test by β‐human Chorionic Gonadotropin

Background and Objectives: Gestational diabetes mellitus (GDM) is a medical problem in pregnancy, and its late diagnosis can cause adverse effects in the mother and fetus. The purpose of this research was to estimate the accuracy parameters of a biomarker for early prediction of gestational diabetes in the absence of a perfect reference standard test.   Methods: This study was conducted in 52...

Application of Proteomics Technologies in the Drug Development Process

Application of adjusted-receiver operating characteristic curve analysis in combination of biomarkers for early detection of gestational diabetes mellitus

Introduction: In medical diagnostic field, evaluation of diagnostic accuracy of biomarkers or tests has always been a matter of concern. In some situations, one biomarker alone may not be sufficiently sensitive and specific for prediction of a disease. However, combining multiple biomarkers may lead to better diagnostic.  The aim of this study was to assess the performance of combination of bio...

Application of Proteomics Technologies in the Drug Development Process

Proteomics Applications in Health: Biomarker and Drug Discovery and Food Industry

Advancing in genome sequencing has greatly propelled the understanding of the living world, however, it is insufficient for full description of a biological system. Focusing on, proteomics has emerged as another large-scale platform for improving the understanding of biology. Proteomic experiments can be used for different aspects of clinical and health sciences such as food technology, biomark...

Proteomics Applications in Health: Biomarker and Drug Discovery and Food Industry

Advancing in genome sequencing has greatly propelled the understanding of the living world, however, it is insufficient for full description of a biological system. Focusing on, proteomics has emerged as another large-scale platform for improving the understanding of biology. Proteomic experiments can be used for different aspects of clinical and health sciences such as food technology, biomark...